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Showing CypComp Card for CC00018: Cyclophosphamide (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:15:52 UTC
Last Updated2019-10-01 21:37:08 UTC
CypComp IDCC00018
Compound Information
NameCyclophosphamide
Structure ImageCmsmoczeivjldb cqszacivsa n
InChIKeyCMSMOCZEIVJLDB-CQSZACIVSA-N
PubChem ID9554282
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantReactantReactantReactantReactantNon-ReactantNon-ReactantReactant
References
  1. Roy P, Yu LJ, Crespi CL, Waxman DJ: Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab Dispos. 1999 Jun;27(6):655-66. [PubMed:10348794 ]
  2. Bohnenstengel F, Hofmann U, Eichelbaum M, Kroemer HK: Characterization of the cytochrome P450 involved in side-chain oxidation of cyclophosphamide in humans. Eur J Clin Pharmacol. 1996;51(3-4):297-301. [PubMed:9010702 ]
Download FileCC00018.sdf