Showing CypComp Card for CC00020: Losartan (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:15:53 UTC
Last Updated2019-10-01 21:37:08 UTC
CypComp IDCC00020
Compound Information
NameLosartan
Structure ImagePsifnnkumbgkdq uhfffaoysa n
InChIKeyPSIFNNKUMBGKDQ-UHFFFAOYSA-N
PubChem ID3961
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Stearns RA, Chakravarty PK, Chen R, Chiu SH: Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily members. Drug Metab Dispos. 1995 Feb;23(2):207-15. [PubMed:7736913 ]
Download FileCC00020.sdf