You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on CypComp Database.
Record Information
Version1.0
Creation Date2019-07-14 16:16:08 UTC
Last Updated2019-10-01 21:37:10 UTC
CypComp IDCC00041
Compound Information
NameCJ-12 458
Structure ImageCvtmennexozzez iowsjchksa n
InChIKeyCVTMENNEXOZZEZ-IOWSJCHKSA-N
PubChem IDNot Available
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantNon-ReactantReactant
References
  1. Obach RS: Cytochrome P450-catalyzed metabolism of ezlopitant alkene (CJ-12,458), a pharmacologically active metabolite of ezlopitant: enzyme kinetics and mechanism of an alkene hydration reaction. Drug Metab Dispos. 2001 Jul;29(7):1057-67. [PubMed:11408374 ]
Download FileCC00041.sdf