Showing CypComp Card for CC00055: Colchicine (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:16:17 UTC
Last Updated2019-10-01 21:37:12 UTC
CypComp IDCC00055
Compound Information
NameColchicine
Structure ImageIakhmkggtnlksz mrxnpfedsa n
InChIKeyIAKHMKGGTNLKSZ-MRXNPFEDSA-N
PubChem ID53278
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Tateishi T, Soucek P, Caraco Y, Guengerich FP, Wood AJ: Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation. Biochem Pharmacol. 1997 Jan 10;53(1):111-6. doi: 10.1016/s0006-2952(96)00693-4. [PubMed:8960070 ]
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