Showing CypComp Card for CC00062: LAAM (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:16:22 UTC
Last Updated2019-10-01 21:37:13 UTC
CypComp IDCC00062
Compound Information
NameLAAM
Structure ImageXbmivrrwgcybtq xmsqkqjnsa n
InChIKeyXBMIVRRWGCYBTQ-XMSQKQJNSA-N
PubChem ID22308
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantReactantReactantNon-ReactantReactantNon-ReactantNon-ReactantReactant
References
  1. Neff JA, Moody DE: Differential N-demethylation of l-alpha-acetylmethadol (LAAM) and norLAAM by cytochrome P450s 2B6, 2C18, and 3A4. Biochem Biophys Res Commun. 2001 Jun 15;284(3):751-6. doi: 10.1006/bbrc.2001.5054. [PubMed:11396966 ]
  2. Moody DE, Alburges ME, Parker RJ, Collins JM, Strong JM: The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone. Drug Metab Dispos. 1997 Dec;25(12):1347-53. [PubMed:9394023 ]
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