Showing CypComp Card for CC00085: Aprepitant (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:16:39 UTC
Last Updated2019-10-01 21:37:16 UTC
CypComp IDCC00085
Compound Information
NameAprepitant
Structure ImageAtalofndeocmkk oitmnorjsa n
InChIKeyATALOFNDEOCMKK-OITMNORJSA-N
PubChem ID135413536
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantNon-ReactantNon-ReactantReactant
References
  1. Sanchez RI, Wang RW, Newton DJ, Bakhtiar R, Lu P, Chiu SH, Evans DC, Huskey SE: Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant. Drug Metab Dispos. 2004 Nov;32(11):1287-92. doi: 10.1124/dmd.104.000216. Epub 2004 Aug 10. [PubMed:15304427 ]
Download FileCC00085.sdf