Showing CypComp Card for CC00116: Torasemide (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:17:03 UTC
Last Updated2019-10-01 21:37:21 UTC
CypComp IDCC00116
Compound Information
NameTorasemide
Structure ImageNgbfqhcmquljnz uhfffaoysa n
InChIKeyNGBFQHCMQULJNZ-UHFFFAOYSA-N
PubChem ID41781
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantReactantReactantNon-ReactantNon-ReactantNon-ReactantNon-Reactant
References
  1. Miners JO, Coulter S, Birkett DJ, Goldstein JA: Torsemide metabolism by CYP2C9 variants and other human CYP2C subfamily enzymes. Pharmacogenetics. 2000 Apr;10(3):267-70. [PubMed:10803683 ]
  2. Miners JO, Rees DL, Valente L, Veronese ME, Birkett DJ: Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism. J Pharmacol Exp Ther. 1995 Mar;272(3):1076-81. [PubMed:7891318 ]
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