Showing CypComp Card for CC00134: Phenacetin (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:17:17 UTC
Last Updated2019-10-01 21:37:23 UTC
CypComp IDCC00134
Compound Information
NamePhenacetin
Structure ImageCpjsueixxcenmm uhfffaoysa n
InChIKeyCPJSUEIXXCENMM-UHFFFAOYSA-N
PubChem ID4754
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantNon-ReactantNon-ReactantReactantReactantReactantReactantReactant
References
  1. Guengerich FP, Parikh A, Yun CH, Kim D, Nakamura K, Notley LM, Gillam EM: What makes P450s work? Searches for answers with known and new P450s. Drug Metab Rev. 2000 Aug-Nov;32(3-4):267-81. doi: 10.1081/DMR-100102334. [PubMed:11139129 ]
  2. Nakajima M, Kobayashi K, Oshima K, Shimada N, Tokudome S, Chiba K, Yokoi T: Activation of phenacetin O-deethylase activity by alpha-naphthoflavone in human liver microsomes. Xenobiotica. 1999 Sep;29(9):885-98. doi: 10.1080/004982599238137. [PubMed:10548449 ]
  3. Kobayashi K, Nakajima M, Oshima K, Shimada N, Yokoi T, Chiba K: Involvement of CYP2E1 as A low-affinity enzyme in phenacetin O-deethylation in human liver microsomes. Drug Metab Dispos. 1999 Aug;27(8):860-5. [PubMed:10421611 ]
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