Showing CypComp Card for CC00137: Haloperidol (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:17:19 UTC
Last Updated2019-10-01 21:37:24 UTC
CypComp IDCC00137
Compound Information
NameHaloperidol
Structure ImageLnepoxffqsencj uhfffaoysa n
InChIKeyLNEPOXFFQSENCJ-UHFFFAOYSA-N
PubChem ID3559
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantReactantReactantReactantReactantNon-ReactantReactant
References
  1. Fang J, McKay G, Song J, Remillrd A, Li X, Midha K: In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes. Drug Metab Dispos. 2001 Dec;29(12):1638-43. [PubMed:11717183 ]
  2. Avent KM, DeVoss JJ, Gillam EM: Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites. Chem Res Toxicol. 2006 Jul;19(7):914-20. doi: 10.1021/tx0600090. [PubMed:16841959 ]
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