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Record Information
Version1.0
Creation Date2019-07-14 16:17:20 UTC
Last Updated2019-10-01 21:37:24 UTC
CypComp IDCC00138
Compound Information
NameCaffeine
Structure ImageRyyvlzvuvijvgh uhfffaoysa n
InChIKeyRYYVLZVUVIJVGH-UHFFFAOYSA-N
PubChem ID2519
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantReactantReactant
References
  1. Lang DH, Rettie AE: In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms. Br J Clin Pharmacol. 2000 Oct;50(4):311-4. doi: 10.1046/j.1365-2125.2000.00265.x. [PubMed:11012553 ]
  2. Ha HR, Chen J, Krahenbuhl S, Follath F: Biotransformation of caffeine by cDNA-expressed human cytochromes P-450. Eur J Clin Pharmacol. 1996;49(4):309-15. [PubMed:8857078 ]
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