You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on CypComp Database.

Showing CypComp Card for CC00145: Phenprocoumon (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:17:26 UTC
Last Updated2019-10-01 21:37:25 UTC
CypComp IDCC00145
Compound Information
NamePhenprocoumon
Structure ImageDqdaygnaktzfiw cybmujfwsa n
InChIKeyDQDAYGNAKTZFIW-CYBMUJFWSA-N
PubChem ID54681545
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantReactantReactantReactantNon-ReactantNon-ReactantReactant
References
  1. Ufer M, Svensson JO, Krausz KW, Gelboin HV, Rane A, Tybring G: Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro. Eur J Clin Pharmacol. 2004 May;60(3):173-82. doi: 10.1007/s00228-004-0740-5. Epub 2004 Mar 31. [PubMed:15054565 ]
  2. Ufer M, Kammerer B, Kahlich R, Kirchheiner J, Yasar U, Brockmoller J, Rane A: Genetic polymorphisms of cytochrome P450 2C9 causing reduced phenprocoumon (S)-7-hydroxylation in vitro and in vivo. Xenobiotica. 2004 Sep;34(9):847-59. doi: 10.1080/00498250400009197. [PubMed:15742978 ]
Download FileCC00145.sdf