Showing CypComp Card for CC00254: 4-Demethylolanzapine (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:18:41 UTC
Last Updated2019-10-01 21:37:37 UTC
CypComp IDCC00254
Compound Information
Name4-Demethylolanzapine
Structure ImageFhpixvhjeizkjw uhfffaoysa n
InChIKeyFHPIXVHJEIZKJW-UHFFFAOYSA-N
PubChem ID135446209
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantNon-ReactantNon-Reactant
References
  1. Ring BJ, Catlow J, Lindsay TJ, Gillespie T, Roskos LK, Cerimele BJ, Swanson SP, Hamman MA, Wrighton SA: Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther. 1996 Feb;276(2):658-66. [PubMed:8632334 ]
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