Showing CypComp Card for CC00261: Cisapride (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:18:47 UTC
Last Updated2019-10-01 21:37:37 UTC
CypComp IDCC00261
Compound Information
NameCisapride
Structure ImageDcsubabjrxzomt rbbkrzogsa n
InChIKeyDCSUBABJRXZOMT-RBBKRZOGSA-N
PubChem ID5311047
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantReactantReactantReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Desta Z, Soukhova N, Morocho AM, Flockhart DA: Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: major role of CYP3A. J Pharmacol Exp Ther. 2001 Aug;298(2):508-20. [PubMed:11454912 ]
  2. Desta Z, Soukhova N, Mahal SK, Flockhart DA: Interaction of cisapride with the human cytochrome P450 system: metabolism and inhibition studies. Drug Metab Dispos. 2000 Jul;28(7):789-800. [PubMed:10859153 ]
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