Record Information
Version1.0
Creation Date2019-07-14 16:19:29 UTC
Last Updated2019-10-01 21:37:46 UTC
CypComp IDCC00325
Compound Information
NameNDMA
Structure ImageUmfjahhvkncglg uhfffaoysa n
InChIKeyUMFJAHHVKNCGLG-UHFFFAOYSA-N
PubChem ID6124
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantNon-ReactantReactantReactantNon-ReactantReactantReactantReactant
References
  1. Bellec G, Dreano Y, Lozach P, Menez JF, Berthou F: Cytochrome P450 metabolic dealkylation of nine N-nitrosodialkylamines by human liver microsomes. Carcinogenesis. 1996 Sep;17(9):2029-34. doi: 10.1093/carcin/17.9.2029. [PubMed:8824531 ]
  2. Kushida H, Fujita K, Suzuki A, Yamada M, Endo T, Nohmi T, Kamataki T: Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH-cytochrome P450 reductase. Carcinogenesis. 2000 Jun;21(6):1227-32. [PubMed:10837014 ]
Download FileCC00325.sdf