Record Information
Version1.0
Creation Date2019-07-14 16:19:30 UTC
Last Updated2019-10-01 21:37:46 UTC
CypComp IDCC00326
Compound Information
NameQuinacrine
Structure ImageGpkjtrjobqgkqk mrxnpfedsa n
InChIKeyGPKJTRJOBQGKQK-MRXNPFEDSA-N
PubChem ID446536
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET: Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein. Drug Metab Dispos. 2006 Jul;34(7):1136-44. doi: 10.1124/dmd.105.008664. Epub 2006 Mar 31. [PubMed:16581945 ]
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