Showing CypComp Card for CC00351: Phenytoin (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:19:48 UTC
Last Updated2019-10-01 21:37:49 UTC
CypComp IDCC00351
Compound Information
NamePhenytoin
Structure ImageCxofvdljlonndw uhfffaoysa n
InChIKeyCXOFVDLJLONNDW-UHFFFAOYSA-N
PubChem ID1775
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantNon-ReactantReactantReactantReactantReactantReactantReactant
References
  1. Komatsu T, Yamazaki H, Asahi S, Gillam EM, Guengerich FP, Nakajima M, Yokoi T: Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4. Drug Metab Dispos. 2000 Nov;28(11):1361-8. [PubMed:11038165 ]
  2. Ono S, Hatanaka T, Hotta H, Satoh T, Gonzalez FJ, Tsutsui M: Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. Xenobiotica. 1996 Jul;26(7):681-93. doi: 10.3109/00498259609046742. [PubMed:8819299 ]
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