Showing CypComp Card for CC00355: Taxol (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:19:53 UTC
Last Updated2019-10-01 21:37:49 UTC
CypComp IDCC00355
Compound Information
NameTaxol
Structure ImageRciniconznjxqf yukvppsfsa n
InChIKeyRCINICONZNJXQF-YUKVPPSFSA-N
PubChem ID14060306
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Sonnichsen DS, Liu Q, Schuetz EG, Schuetz JD, Pappo A, Relling MV: Variability in human cytochrome P450 paclitaxel metabolism. J Pharmacol Exp Ther. 1995 Nov;275(2):566-75. [PubMed:7473140 ]
  2. Harris JW, Rahman A, Kim BR, Guengerich FP, Collins JM: Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res. 1994 Aug 1;54(15):4026-35. [PubMed:7913410 ]
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