Showing CypComp Card for CC00357: all-trans-Retinol (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:19:55 UTC
Last Updated2019-10-01 21:37:49 UTC
CypComp IDCC00357
Compound Information
Nameall-trans-Retinol
Structure ImageFpipgxgpppqfeq ovsjkpmpsa n
InChIKeyFPIPGXGPPPQFEQ-OVSJKPMPSA-N
PubChem ID445354
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantNon-ReactantReactantReactantReactantReactantNon-ReactantReactant
References
  1. Chen H, Howald WN, Juchau MR: Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes. Drug Metab Dispos. 2000 Mar;28(3):315-22. [PubMed:10681376 ]
  2. Leo MA, Lasker JM, Raucy JL, Kim CI, Black M, Lieber CS: Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8. Arch Biochem Biophys. 1989 Feb 15;269(1):305-12. doi: 10.1016/0003-9861(89)90112-4. [PubMed:2916844 ]
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