Record Information
Version1.0
Creation Date2019-07-14 16:20:11 UTC
Last Updated2019-10-01 21:37:52 UTC
CypComp IDCC00379
Compound Information
NameAntipyrine
Structure ImageVeqoalnaajbpny uhfffaoysa n
InChIKeyVEQOALNAAJBPNY-UHFFFAOYSA-N
PubChem ID2206
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantReactantReactantReactantNon-ReactantReactantReactantReactant
References
  1. Engel G, Hofmann U, Heidemann H, Cosme J, Eichelbaum M: Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin Pharmacol Ther. 1996 Jun;59(6):613-23. doi: 10.1016/S0009-9236(96)90001-6. [PubMed:8681486 ]
  2. Sharer JE, Wrighton SA: Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine. Drug Metab Dispos. 1996 Apr;24(4):487-94. [PubMed:8801065 ]
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