Showing CypComp Card for CC00415: Bufuralol (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:20:35 UTC
Last Updated2019-10-01 21:37:56 UTC
CypComp IDCC00415
Compound Information
NameBufuralol
Structure ImageSsebtppfllcumn cybmujfwsa n
InChIKeySSEBTPPFLLCUMN-CYBMUJFWSA-N
PubChem ID11276993
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantReactantNon-ReactantReactant
References
  1. Yamazaki H, Guo Z, Persmark M, Mimura M, Inoue K, Guengerich FP, Shimada T: Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol Pharmacol. 1994 Sep;46(3):568-77. [PubMed:7935340 ]
  2. Narimatsu S, Takemi C, Kuramoto S, Tsuzuki D, Hichiya H, Tamagake K, Yamamoto S: Stereoselectivity in the oxidation of bufuralol, a chiral substrate, by human cytochrome P450s. Chirality. 2003 May 5;15(4):333-9. doi: 10.1002/chir.10212. [PubMed:12666241 ]
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