Showing CypComp Card for CC00444: Mexiletine (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:20:56 UTC
Last Updated2019-10-01 21:38:00 UTC
CypComp IDCC00444
Compound Information
NameMexiletine
Structure ImageVlpiatfuuwwmkc snvbaglbsa n
InChIKeyVLPIATFUUWWMKC-SNVBAGLBSA-N
PubChem ID180621
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantReactantNon-ReactantNon-ReactantNon-ReactantReactantReactantNon-Reactant
References
  1. Nakajima M, Kobayashi K, Shimada N, Tokudome S, Yamamoto T, Kuroiwa Y: Involvement of CYP1A2 in mexiletine metabolism. Br J Clin Pharmacol. 1998 Jul;46(1):55-62. doi: 10.1046/j.1365-2125.1998.00048.x. [PubMed:9690950 ]
  2. Labbe L, Abolfathi Z, Lessard E, Pakdel H, Beaune P, Turgeon J: Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine. Xenobiotica. 2003 Jan;33(1):13-25. doi: 10.1080/0049825021000017948. [PubMed:12519691 ]
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