Showing CypComp Card for CC00445: SERM-I (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:20:56 UTC
Last Updated2019-10-01 21:38:00 UTC
CypComp IDCC00445
Compound Information
NameSERM-I
Structure ImageTwznctcqagrugq rrpnlbnlsa n
InChIKeyTWZNCTCQAGRUGQ-RRPNLBNLSA-N
PubChem ID448577
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Zhang Z, Chen Q, Li Y, Doss GA, Dean BJ, Ngui JS, Silva Elipe M, Kim S, Wu JY, Dininno F, Hammond ML, Stearns RA, Evans DC, Baillie TA, Tang W: In vitro bioactivation of dihydrobenzoxathiin selective estrogen receptor modulators by cytochrome P450 3A4 in human liver microsomes: formation of reactive iminium and quinone type metabolites. Chem Res Toxicol. 2005 Apr;18(4):675-85. doi: 10.1021/tx0496789. [PubMed:15833027 ]
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