Showing CypComp Card for CC00449: FK-506 (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:20:59 UTC
Last Updated2019-10-01 21:38:00 UTC
CypComp IDCC00449
Compound Information
NameFK-506
Structure ImageQjjxyppxxyfbgm lfznuxcksa n
InChIKeyQJJXYPPXXYFBGM-LFZNUXCKSA-N
PubChem ID445643
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Vincent SH, Karanam BV, Painter SK, Chiu SH: In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. Arch Biochem Biophys. 1992 May 1;294(2):454-60. doi: 10.1016/0003-9861(92)90711-5. [PubMed:1373595 ]
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