Showing CypComp Card for CC00478: Flutamide (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:21:19 UTC
Last Updated2019-10-01 21:38:04 UTC
CypComp IDCC00478
Compound Information
NameFlutamide
Structure ImageMkxkfyhwdhiyrv uhfffaoysa n
InChIKeyMKXKFYHWDHIYRV-UHFFFAOYSA-N
PubChem ID3397
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantNon-ReactantNon-ReactantReactantReactantNon-ReactantNon-ReactantNon-Reactant
References
  1. Shet MS, McPhaul M, Fisher CW, Stallings NR, Estabrook RW: Metabolism of the antiandrogenic drug (Flutamide) by human CYP1A2. Drug Metab Dispos. 1997 Nov;25(11):1298-303. [PubMed:9351907 ]
  2. Goda R, Nagai D, Akiyama Y, Nishikawa K, Ikemoto I, Aizawa Y, Nagata K, Yamazoe Y: Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients. Drug Metab Dispos. 2006 May;34(5):828-35. doi: 10.1124/dmd.105.008623. Epub 2006 Feb 28. [PubMed:16507648 ]
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