Showing CypComp Card for CC00497: Lisofylline (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:21:32 UTC
Last Updated2019-10-01 21:38:05 UTC
CypComp IDCC00497
Compound Information
NameLisofylline
Structure ImageNsmxqknuppxbrg secbinfhsa n
InChIKeyNSMXQKNUPPXBRG-SECBINFHSA-N
PubChem ID501254
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactant
References
  1. Lee SH, Slattery JT: Cytochrome P450 isozymes involved in lisofylline metabolism to pentoxifylline in human liver microsomes. Drug Metab Dispos. 1997 Dec;25(12):1354-8. [PubMed:9394024 ]
  2. Shin HS, Slattery JT: CYP3A4-mediated oxidation of lisofylline to lisofylline 4,5-diol in human liver microsomes. J Pharm Sci. 1998 Mar;87(3):390-3. doi: 10.1021/js970382f. [PubMed:9523995 ]
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