Showing CypComp Card for CC00512: Dapsone (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:21:40 UTC
Last Updated2019-10-01 21:38:07 UTC
CypComp IDCC00512
Compound Information
NameDapsone
Structure ImageMqjkpegwnlwltk uhfffaoysa n
InChIKeyMQJKPEGWNLWLTK-UHFFFAOYSA-N
PubChem ID2955
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantReactantReactantReactantNon-ReactantReactantReactant
References
  1. Winter HR, Wang Y, Unadkat JD: CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone. Drug Metab Dispos. 2000 Aug;28(8):865-8. [PubMed:10901692 ]
  2. Mitra AK, Thummel KE, Kalhorn TF, Kharasch ED, Unadkat JD, Slattery JT: Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo. Clin Pharmacol Ther. 1995 Nov;58(5):556-66. doi: 10.1016/0009-9236(95)90176-0. [PubMed:7586950 ]
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