Showing CypComp Card for CC00525: Gepirone (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:21:49 UTC
Last Updated2019-10-01 21:38:09 UTC
CypComp IDCC00525
Compound Information
NameGepirone
Structure ImageQoigkgmmagjznz uhfffaoysa n
InChIKeyQOIGKGMMAGJZNZ-UHFFFAOYSA-N
PubChem ID55191
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantNon-ReactantReactant
References
  1. von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Fogelman SM, Harmatz JS, Kramer SJ, Fabre LF, Shader RI: Gepirone and 1-(2-pyrimidinyl)-piperazine in vitro: human cytochromes mediating transformation and cytochrome inhibitory effects. Psychopharmacology (Berl). 1998 Dec;140(3):293-9. [PubMed:9877009 ]
  2. Greenblatt DJ, Von Moltke LL, Giancarlo GM, Garteiz DA: Human cytochromes mediating gepirone biotransformation at low substrate concentrations. Biopharm Drug Dispos. 2003 Mar;24(2):87-94. doi: 10.1002/bdd.340. [PubMed:12619053 ]
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