Record Information
Version1.0
Creation Date2019-07-14 16:21:50 UTC
Last Updated2019-10-01 21:38:09 UTC
CypComp IDCC00526
Compound Information
NamePropofol
Structure ImageOlbcvfgfozpwhh uhfffaoysa n
InChIKeyOLBCVFGFOZPWHH-UHFFFAOYSA-N
PubChem ID4943
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantReactantReactantReactantReactantReactantReactantReactant
References
  1. Court MH, Duan SX, Hesse LM, Venkatakrishnan K, Greenblatt DJ: Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes. Anesthesiology. 2001 Jan;94(1):110-9. doi: 10.1097/00000542-200101000-00021. [PubMed:11135730 ]
  2. Guitton J, Buronfosse T, Desage M, Flinois JP, Perdrix JP, Brazier JL, Beaune P: Possible involvement of multiple human cytochrome P450 isoforms in the liver metabolism of propofol. Br J Anaesth. 1998 Jun;80(6):788-95. doi: 10.1093/bja/80.6.788. [PubMed:9771309 ]
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