Showing CypComp Card for CC00553: Voreloxin (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:22:12 UTC
Last Updated2019-10-01 21:38:13 UTC
CypComp IDCC00553
Compound Information
NameVoreloxin
Structure ImageXzafzxjxzhrnaq chwsqxevsa n
InChIKeyXZAFZXJXZHRNAQ-CHWSQXEVSA-N
PubChem ID9865776
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantNon-ReactantReactant
References
  1. Evanchik MJ, Allen D, Yoburn JC, Silverman JA, Hoch U: Metabolism of (+)-1,4-dihydro-7-(trans-3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiaz olyl)-1,8-naphthyridine-3-carboxylic acid (voreloxin; formerly SNS-595), a novel replication-dependent DNA-damaging agent. Drug Metab Dispos. 2009 Mar;37(3):594-601. doi: 10.1124/dmd.108.023432. Epub 2008 Dec 12. [PubMed:19074528 ]
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