Showing CypComp Card for CC00563: Chlorzoxazone (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:22:18 UTC
Last Updated2019-10-01 21:38:14 UTC
CypComp IDCC00563
Compound Information
NameChlorzoxazone
Structure ImageTzfwdzfkrbeliq uhfffaoysa n
InChIKeyTZFWDZFKRBELIQ-UHFFFAOYSA-N
PubChem ID2733
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantReactantReactantNon-ReactantReactantReactantReactantReactantReactant
References
  1. Shimada T, Tsumura F, Yamazaki H: Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes. Drug Metab Dispos. 1999 Nov;27(11):1274-80. [PubMed:10534312 ]
  2. Draper AJ, Madan A, Latham J, Parkinson A: Development of a non-high pressure liquid chromatography assay to determine [14C]chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes. Drug Metab Dispos. 1998 Apr;26(4):305-12. [PubMed:9531516 ]
Download FileCC00563.sdf