Showing CypComp Card for CC00620: Trimethadione (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:22:57 UTC
Last Updated2019-10-01 21:38:20 UTC
CypComp IDCC00620
Compound Information
NameTrimethadione
Structure ImageIryjrgciqbghiv uhfffaoysa n
InChIKeyIRYJRGCIQBGHIV-UHFFFAOYSA-N
PubChem ID5576
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantReactantReactantNon-ReactantNon-ReactantReactantReactant
References
  1. Kurata N, Nishimura Y, Iwase M, Fischer NE, Tang BK, Inaba T, Yasuhara H: Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1. Xenobiotica. 1998 Nov;28(11):1041-7. doi: 10.1080/004982598238930. [PubMed:9879636 ]
  2. Tanaka E, Kurata N, Yasuhara H: Involvement of cytochrome P450 2C9, 2E1 and 3A4 in trimethadione N-demethylation in human microsomes. J Clin Pharm Ther. 2003 Dec;28(6):493-6. [PubMed:14651673 ]
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