Showing CypComp Card for CC00639: Bupropion (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:23:08 UTC
Last Updated2019-10-01 21:38:22 UTC
CypComp IDCC00639
Compound Information
NameBupropion
Structure ImageSnppwiuozrmyny secbinfhsa n
InChIKeySNPPWIUOZRMYNY-SECBINFHSA-N
PubChem ID688387
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantReactant
References
  1. Faucette SR, Hawke RL, Shord SS, Lecluyse EL, Lindley CM: Evaluation of the contribution of cytochrome P450 3A4 to human liver microsomal bupropion hydroxylation. Drug Metab Dispos. 2001 Aug;29(8):1123-9. [PubMed:11454731 ]
  2. Faucette SR, Hawke RL, Lecluyse EL, Shord SS, Yan B, Laethem RM, Lindley CM: Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity. Drug Metab Dispos. 2000 Oct;28(10):1222-30. [PubMed:10997944 ]
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