Showing CypComp Card for CC00644: Omeprazole (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:23:11 UTC
Last Updated2019-10-01 21:38:23 UTC
CypComp IDCC00644
Compound Information
NameOmeprazole
Structure ImageSubdbmmjdzjvos deossopvsa n
InChIKeySUBDBMMJDZJVOS-DEOSSOPVSA-N
PubChem ID9568614
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantReactantNon-ReactantReactantReactantReactantNon-ReactantNon-ReactantReactant
References
  1. Abelo A, Andersson TB, Antonsson M, Naudot AK, Skanberg I, Weidolf L: Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes. Drug Metab Dispos. 2000 Aug;28(8):966-72. [PubMed:10901708 ]
  2. Karam WG, Goldstein JA, Lasker JM, Ghanayem BI: Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes. Drug Metab Dispos. 1996 Oct;24(10):1081-7. [PubMed:8894508 ]
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