Showing CypComp Card for CC00646: Bunitrolol (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:23:12 UTC
Last Updated2019-10-01 21:38:23 UTC
CypComp IDCC00646
Compound Information
NameBunitrolol
Structure ImageVcvqsrcyskkpba gfccvegcsa n
InChIKeyVCVQSRCYSKKPBA-GFCCVEGCSA-N
PubChem ID72710712
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
Non-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantNon-ReactantReactantNon-ReactantNon-Reactant
References
  1. Narimatsu S, Kato R, Horie T, Ono S, Tsutsui M, Yabusaki Y, Ohmori S, Kitada M, Ichioka T, Shimada N, Kato R, Ishikawa T: Enantioselectivity of bunitrolol 4-hydroxylation is reversed by the change of an amino acid residue from valine to methionine at position 374 of cytochrome P450-2D6. Chirality. 1999;11(1):1-9. doi: 10.1002/(SICI)1520-636X(1999)11:1<1::AID-CHIR1>3.0.CO;2-E. [PubMed:9914647 ]
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