Showing CypComp Card for CC00653: Amiodarone (CypReact Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:23:17 UTC
Last Updated2019-10-01 21:38:24 UTC
CypComp IDCC00653
Compound Information
NameAmiodarone
Structure ImageIyiklhrqxlhmjq uhfffaoysa n
InChIKeyIYIKLHRQXLHMJQ-UHFFFAOYSA-N
PubChem ID2157
CypCompound Information
SetCypReact Training Set
Reactant Statuses
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
ReactantNon-ReactantNon-ReactantReactantNon-ReactantReactantReactantNon-ReactantReactant
References
  1. Ohyama K, Nakajima M, Nakamura S, Shimada N, Yamazaki H, Yokoi T: A significant role of human cytochrome P450 2C8 in amiodarone N-deethylation: an approach to predict the contribution with relative activity factor. Drug Metab Dispos. 2000 Nov;28(11):1303-10. [PubMed:11038157 ]
  2. Fabre G, Julian B, Saint-Aubert B, Joyeux H, Berger Y: Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions. Drug Metab Dispos. 1993 Nov-Dec;21(6):978-85. [PubMed:7905403 ]
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