Showing CypComp Card for CC01809: 3-Cyano-7-ethoxycoumarin (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:35:00 UTC
Last Updated2019-10-01 21:40:49 UTC
CypComp IDCC01809
Compound Information
Name3-Cyano-7-ethoxycoumarin
Structure ImageYafghmiafyqscf uhfffaoysa n
InChIKeyYAFGHMIAFYQSCF-UHFFFAOYSA-N
PubChem ID164045
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <5,H;Oxidation;R1>
  • <5,4;Cleavage;R1>
  • <5,H;Oxidation;R1>
  • <5,4;Cleavage;R1>
  • <5,H;Oxidation;R1>
  • <5,4;Cleavage;R1>
  • Not Available
  • <5,H;Oxidation;R1>
  • <5,4;Cleavage;R1>
  • <5,H;Oxidation;R1>
  • <5,4;Cleavage;R1>
  • <5,H;Oxidation;R1>
  • <5,4;Cleavage;R1>
  • <5,H;Oxidation;R1>
  • <5,4;Cleavage;R1>
  • Not Available
References
  1. Donato MT, Jimenez N, Castell JV, Gomez-Lechon MJ: Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab Dispos. 2004 Jul;32(7):699-706. doi: 10.1124/dmd.32.7.699. [PubMed:15205384 ]
  2. Ekins S, Vandenbranden M, Ring BJ, Gillespie JS, Yang TJ, Gelboin HV, Wrighton SA: Further characterization of the expression in liver and catalytic activity of CYP2B6. J Pharmacol Exp Ther. 1998 Sep;286(3):1253-9. [PubMed:9732386 ]
  3. Ghosal A, Hapangama N, Yuan Y, Lu X, Horne D, Patrick JE, Zbaida S: Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes. Biopharm Drug Dispos. 2003 Dec;24(9):375-84. doi: 10.1002/bdd.374. [PubMed:14689466 ]
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