Showing CypComp Card for CC01820: 6-Aminochrysene (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:35:04 UTC
Last Updated2019-10-01 21:40:51 UTC
CypComp IDCC01820
Compound Information
Name6-Aminochrysene
Structure ImageKivuhcnvdwyunp uhfffaoysa n
InChIKeyKIVUHCNVDWYUNP-UHFFFAOYSA-N
PubChem ID17534
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <10,H;Hydroxylation;R1>
  • <13,17;Epoxidation;R2>
  • <10,H;Hydroxylation;R1>
  • <10,H;Hydroxylation;R1>
  • <13,17;Epoxidation;R2>
  • Not Available
  • Not Available
  • Not Available
  • <10,H;Hydroxylation;R1>
  • <13,17;Epoxidation;R2>
  • Not Available
  • <10,H;Hydroxylation;R1>
  • <13,17;Epoxidation;R2>
References
  1. Yamazaki H, Mimura M, Oda Y, Inui Y, Shiraga T, Iwasaki K, Guengerich FP, Shimada T: Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes. Carcinogenesis. 1993 Jul;14(7):1271-8. doi: 10.1093/carcin/14.7.1271. [PubMed:8330339 ]
  2. Yun CH, Shimada T, Guengerich FP: Purification and characterization of human liver microsomal cytochrome P-450 2A6. Mol Pharmacol. 1991 Nov;40(5):679-85. [PubMed:1944238 ]
  3. Koehl W, Amin S, Staretz ME, Ueng YF, Yamazaki H, Tateishi T, Guengerich FP, Hecht SS: Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes. Cancer Res. 1996 Jan 15;56(2):316-24. [PubMed:8542586 ]
Download FileCC01820.sdf