Showing CypComp Card for CC01874: ABT-438 (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:35:24 UTC
Last Updated2019-10-01 21:40:57 UTC
CypComp IDCC01874
Compound Information
NameABT-438
Structure ImageXrxfskokcipngh lbprgkrzsa n
InChIKeyXRXFSKOKCIPNGH-LBPRGKRZSA-N
PubChem ID66833621
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <7,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • Not Available
  • <7,H;Hydroxylation;R1>
  • <7,H;Hydroxylation;R1>
  • <7,H;Hydroxylation;R1>
  • <7,H;Hydroxylation;R1>
  • <7,H;Hydroxylation;R1>
References
  1. Machinist JM, Mayer MD, Shet MS, Ferrero JL, Rodrigues AD: Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193. Drug Metab Dispos. 1995 Oct;23(10):1163-74. [PubMed:8654206 ]
Download FileCC01874.sdf