Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:35:27 UTC |
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Last Updated | 2019-10-01 21:40:58 UTC |
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CypComp ID | CC01882 |
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Compound Information |
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Name | all-trans-Retinol |
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Structure Image | |
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InChIKey | FPIPGXGPPPQFEQ-OVSJKPMPSA-N |
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PubChem ID | 445354 |
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CypCompound Information |
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Set | CypBoM Training Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | - <20,21;Oxidation;R1>
- <3,H;Hydroxylation;R2>
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References | - Leo MA, Lasker JM, Raucy JL, Kim CI, Black M, Lieber CS: Metabolism of retinol and retinoic acid by human liver cytochrome P450IIC8. Arch Biochem Biophys. 1989 Feb 15;269(1):305-12. doi: 10.1016/0003-9861(89)90112-4. [PubMed:2916844 ]
- Chen H, Howald WN, Juchau MR: Biosynthesis of all-trans-retinoic acid from all-trans-retinol: catalysis of all-trans-retinol oxidation by human P-450 cytochromes. Drug Metab Dispos. 2000 Mar;28(3):315-22. [PubMed:10681376 ]
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Download File | CC01882.sdf |
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