Showing CypComp Card for CC01908: Chlorpropamide (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:35:39 UTC
Last Updated2019-10-01 21:41:02 UTC
CypComp IDCC01908
Compound Information
NameChlorpropamide
Structure ImageRkwgiwycvpqpmf uhfffaoysa n
InChIKeyRKWGIWYCVPQPMF-UHFFFAOYSA-N
PubChem ID2727
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
  • Not Available
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
  • <4,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R2>
References
  1. Shon JH, Yoon YR, Kim MJ, Kim KA, Lim YC, Liu KH, Shin DH, Lee CH, Cha IJ, Shin JG: Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism. Br J Clin Pharmacol. 2005 May;59(5):552-63. doi: 10.1111/j.1365-2125.2005.02364.x. [PubMed:15842554 ]
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