Showing CypComp Card for CC01910: Chlorzoxazone (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:35:40 UTC
Last Updated2019-10-01 21:41:02 UTC
CypComp IDCC01910
Compound Information
NameChlorzoxazone
Structure ImageTzfwdzfkrbeliq uhfffaoysa n
InChIKeyTZFWDZFKRBELIQ-UHFFFAOYSA-N
PubChem ID2733
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <3,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R1>
  • Not Available
  • <3,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R1>
  • <3,H;Hydroxylation;R1>
References
  1. Shimada T, Tsumura F, Yamazaki H: Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes. Drug Metab Dispos. 1999 Nov;27(11):1274-80. [PubMed:10534312 ]
  2. Draper AJ, Madan A, Latham J, Parkinson A: Development of a non-high pressure liquid chromatography assay to determine [14C]chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes. Drug Metab Dispos. 1998 Apr;26(4):305-12. [PubMed:9531516 ]
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