You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on CypComp Database.
Record Information
Version1.0
Creation Date2019-07-14 16:35:40 UTC
Last Updated2019-10-01 21:41:02 UTC
CypComp IDCC01911
Compound Information
NameCilostazol
Structure ImageRrguktpigviekm uhfffaoysa n
InChIKeyRRGUKTPIGVIEKM-UHFFFAOYSA-N
PubChem ID2754
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <14,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <27,H;Hydroxylation;R1>
  • <14,H;Hydroxylation;R1>
  • Not Available
  • <27,H;Hydroxylation;R1>
  • <14,H;Hydroxylation;R2>
References
  1. Suri A, Forbes WP, Bramer SL: Effects of CYP3A inhibition on the metabolism of cilostazol. Clin Pharmacokinet. 1999;37 Suppl 2:61-8. doi: 10.2165/00003088-199937002-00007. [PubMed:10702888 ]
  2. Abbas R, Chow CP, Browder NJ, Thacker D, Bramer SL, Fu CJ, Forbes W, Odomi M, Flockhart DA: In vitro metabolism and interaction of cilostazol with human hepatic cytochrome P450 isoforms. Hum Exp Toxicol. 2000 Mar;19(3):178-84. doi: 10.1191/096032700678827717. [PubMed:10889516 ]
Download FileCC01911.sdf