Showing CypComp Card for CC01933: Diphenhydramine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:35:48 UTC
Last Updated2019-10-01 21:41:05 UTC
CypComp IDCC01933
Compound Information
NameDiphenhydramine
Structure ImageZzvuwrfhkojyth uhfffaoysa n
InChIKeyZZVUWRFHKOJYTH-UHFFFAOYSA-N
PubChem ID3100
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <9,7;Cleavage;R2>
  • <9,H;Oxidation;R2>
  • Not Available
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <9,7;Cleavage;R2>
  • <9,H;Oxidation;R2>
  • Not Available
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <9,7;Cleavage;R2>
  • <9,H;Oxidation;R2>
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <9,7;Cleavage;R2>
  • <9,H;Oxidation;R2>
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <9,7;Cleavage;R2>
  • <9,H;Oxidation;R2>
  • Not Available
  • <8,7;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <9,7;Cleavage;R2>
  • <9,H;Oxidation;R2>
References
  1. Akutsu T, Kobayashi K, Sakurada K, Ikegaya H, Furihata T, Chiba K: Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation. Drug Metab Dispos. 2007 Jan;35(1):72-8. doi: 10.1124/dmd.106.012088. Epub 2006 Oct 4. [PubMed:17020955 ]
Download FileCC01933.sdf