Showing CypComp Card for CC01935: Domperidone (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:35:50 UTC
Last Updated2019-10-01 21:41:05 UTC
CypComp IDCC01935
Compound Information
NameDomperidone
Structure ImageFgxwkszfvqustl uhfffaoysa n
InChIKeyFGXWKSZFVQUSTL-UHFFFAOYSA-N
PubChem ID3151
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <30,H;Hydroxylation;R1>
  • Not Available
  • <30,H;Hydroxylation;R1>
  • <30,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • <30,H;Hydroxylation;R1>
  • Not Available
  • <30,H;Hydroxylation;R1>
  • <18,16;Cleavage;R2>
  • <18,H;Oxidation;R2>
References
  1. Ward BA, Morocho A, Kandil A, Galinsky RE, Flockhart DA, Desta Z: Characterization of human cytochrome P450 enzymes catalyzing domperidone N-dealkylation and hydroxylation in vitro. Br J Clin Pharmacol. 2004 Sep;58(3):277-87. doi: 10.1111/j.1365-2125.2004.02156.x. [PubMed:15327587 ]
Download FileCC01935.sdf