Record Information |
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Version | 1.0 |
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Creation Date | 2019-07-14 16:35:52 UTC |
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Last Updated | 2019-10-01 21:41:05 UTC |
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CypComp ID | CC01938 |
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Compound Information |
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Name | Efavirenz |
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Structure Image | |
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InChIKey | XPOQHMRABVBWPR-ZDUSSCGKSA-N |
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PubChem ID | 64139 |
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CypCompound Information |
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Set | CypBoM Training Set |
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Bonds of Metabolism (BoMs) | CYP1A2 | CYP2A6 | CYP2B6 | CYP2C8 | CYP2C9 | CYP2C19 | CYP2D6 | CYP2E1 | CYP3A4 | | | | | | | | | |
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References | - Ward BA, Gorski JC, Jones DR, Hall SD, Flockhart DA, Desta Z: The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. J Pharmacol Exp Ther. 2003 Jul;306(1):287-300. doi: 10.1124/jpet.103.049601. Epub 2003 Apr 3. [PubMed:12676886 ]
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Download File | CC01938.sdf |
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