Showing CypComp Card for CC01972: Loratadine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:04 UTC
Last Updated2019-10-01 21:41:09 UTC
CypComp IDCC01972
Compound Information
NameLoratadine
Structure ImageJccnymkqosznpw uhfffaoysa n
InChIKeyJCCNYMKQOSZNPW-UHFFFAOYSA-N
PubChem ID3957
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <24,H;Hydroxylation;R1>
  • Not Available
  • <24,H;Hydroxylation;R1>
  • <24,H;Hydroxylation;R1>
  • <24,H;Hydroxylation;R1>
  • <24,H;Hydroxylation;R1>
  • <24,H;Hydroxylation;R1>
  • Not Available
  • <24,H;Hydroxylation;R1>
References
  1. Ghosal A, Gupta S, Ramanathan R, Yuan Y, Lu X, Su AD, Alvarez N, Zbaida S, Chowdhury SK, Alton KB: Metabolism of loratadine and further characterization of its in vitro metabolites. Drug Metab Lett. 2009 Aug;3(3):162-70. Epub 2009 Aug 1. [PubMed:19702548 ]
  2. Zhou SF: Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II. Clin Pharmacokinet. 2009;48(12):761-804. doi: 10.2165/11318070-000000000-00000. [PubMed:19902987 ]
Download FileCC01972.sdf