Showing CypComp Card for CC01986: Methyleugenol (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:09 UTC
Last Updated2019-10-01 21:41:11 UTC
CypComp IDCC01986
Compound Information
NameMethyleugenol
Structure ImageZyemgpiyfijgtp uhfffaoysa n
InChIKeyZYEMGPIYFIJGTP-UHFFFAOYSA-N
PubChem ID7127
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <11,H;Hydroxylation;R1>
  • Not Available
  • Not Available
  • Not Available
  • <11,H;Hydroxylation;R1>
  • <11,H;Hydroxylation;R1>
  • <11,H;Hydroxylation;R1>
  • Not Available
  • Not Available
References
  1. Jeurissen SM, Bogaards JJ, Boersma MG, ter Horst JP, Awad HM, Fiamegos YC, van Beek TA, Alink GM, Sudholter EJ, Cnubben NH, Rietjens IM: Human cytochrome p450 enzymes of importance for the bioactivation of methyleugenol to the proximate carcinogen 1'-hydroxymethyleugenol. Chem Res Toxicol. 2006 Jan;19(1):111-6. doi: 10.1021/tx050267h. [PubMed:16411663 ]
  2. Gardner I, Wakazono H, Bergin P, de Waziers I, Beaune P, Kenna JG, Caldwell J: Cytochrome P450 mediated bioactivation of methyleugenol to 1'-hydroxymethyleugenol in Fischer 344 rat and human liver microsomes. Carcinogenesis. 1997 Sep;18(9):1775-83. doi: 10.1093/carcin/18.9.1775. [PubMed:9328175 ]
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