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Record Information
Version1.0
Creation Date2019-07-14 16:36:09 UTC
Last Updated2019-10-01 21:41:11 UTC
CypComp IDCC01987
Compound Information
NameMetoclopramide
Structure ImageTtwjbbzezqicbi uhfffaoysa n
InChIKeyTTWJBBZEZQICBI-UHFFFAOYSA-N
PubChem ID4168
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <17,16;Cleavage;R1>
  • <17,H;Oxidation;R1>
  • <18,16;Cleavage;R2>
  • <18,H;Oxidation;R2>
  • Not Available
  • Not Available
  • <17,16;Cleavage;R1>
  • <17,H;Oxidation;R1>
  • <18,16;Cleavage;R2>
  • <18,H;Oxidation;R2>
  • Not Available
  • <17,16;Cleavage;R1>
  • <17,H;Oxidation;R1>
  • <18,16;Cleavage;R2>
  • <18,H;Oxidation;R2>
  • <17,16;Cleavage;R1>
  • <17,H;Oxidation;R1>
  • <18,16;Cleavage;R2>
  • <18,H;Oxidation;R2>
  • Not Available
  • <17,16;Cleavage;R1>
  • <17,H;Oxidation;R1>
  • <18,16;Cleavage;R2>
  • <18,H;Oxidation;R2>
References
  1. Desta Z, Wu GM, Morocho AM, Flockhart DA: The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6. Drug Metab Dispos. 2002 Mar;30(3):336-43. doi: 10.1124/dmd.30.3.336. [PubMed:11854155 ]
Download FileCC01987.sdf