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Showing CypComp Card for CC01989: Mirtazapine (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:10 UTC
Last Updated2019-10-01 21:41:12 UTC
CypComp IDCC01989
Compound Information
NameMirtazapine
Structure ImageRonzaemnmfqxra mrxnpfedsa n
InChIKeyRONZAEMNMFQXRA-MRXNPFEDSA-N
PubChem ID3085218
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <15,9;Cleavage;R1>
  • <15,H;Oxidation;R1>
  • <18,H;Hydroxylation;R2>
  • <9,N;Oxidation;R3>
  • Not Available
  • Not Available
  • <15,9;Cleavage;R1>
  • <15,H;Oxidation;R1>
  • <18,H;Hydroxylation;R1>
  • Not Available
  • <18,H;Hydroxylation;R1>
  • <15,9;Cleavage;R1>
  • <15,H;Oxidation;R1>
  • Not Available
  • <15,9;Cleavage;R1>
  • <15,H;Oxidation;R1>
  • <18,H;Hydroxylation;R2>
  • <9,N;Oxidation;R3>
References
  1. Stormer E, von Moltke LL, Shader RI, Greenblatt DJ: Metabolism of the antidepressant mirtazapine in vitro: contribution of cytochromes P-450 1A2, 2D6, and 3A4. Drug Metab Dispos. 2000 Oct;28(10):1168-75. [PubMed:10997935 ]
Download FileCC01989.sdf