Showing CypComp Card for CC01991: ML-3603 (CypBoM Training Set)

Record Information
Version1.0
Creation Date2019-07-14 16:36:10 UTC
Last Updated2019-10-01 21:41:12 UTC
CypComp IDCC01991
Compound Information
NameML-3603
Structure ImageLdyvdkcsgkmmhs dhmkhtpvsa n
InChIKeyLDYVDKCSGKMMHS-DHMKHTPVSA-N
PubChem ID53239057
CypCompound Information
SetCypBoM Training Set
Bonds of Metabolism (BoMs)
CYP1A2CYP2A6CYP2B6CYP2C8CYP2C9CYP2C19CYP2D6CYP2E1CYP3A4
  • <1,S;Oxidation;R1>
  • Not Available
  • Not Available
  • Not Available
  • Not Available
  • <1,S;Oxidation;R1>
  • <1,S;Oxidation;R1>
  • Not Available
  • <8,4;Cleavage;R1>
  • <8,H;Oxidation;R1>
  • <1,S;Oxidation;R2>
  • <7,N;Oxidation;R3>
References
  1. Kammerer B, Scheible H, Albrecht W, Gleiter CH, Laufer S: Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-pheny lethyl)-amine), a 4-Pyridinylimidazole-type p38 mitogen-activated protein kinase inhibitor. Drug Metab Dispos. 2007 Jun;35(6):875-83. doi: 10.1124/dmd.106.013409. Epub 2007 Mar 7. [PubMed:17344341 ]
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